Issue 6, 2013

A controllable gene expression system in liposomes that includes a positive feedback loop

Abstract

We introduced a positive feedback loop into a LacI-dependent gene expression system in lipid vesicles, producing a cell-like system that senses and responds to an external signal with a high signal-to-noise ratio. This fully reconstituted system will be a useful tool in future applications in in vitro synthetic biology.

Graphical abstract: A controllable gene expression system in liposomes that includes a positive feedback loop

Supplementary files

Article information

Article type
Communication
Submitted
23 Jan 2013
Accepted
12 Mar 2013
First published
12 Mar 2013

Mol. BioSyst., 2013,9, 1282-1285

A controllable gene expression system in liposomes that includes a positive feedback loop

S. Kobori, N. Ichihashi, Y. Kazuta and T. Yomo, Mol. BioSyst., 2013, 9, 1282 DOI: 10.1039/C3MB70032A

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